iMATCH to benefit from £17.9m additional funding for Advanced Therapy Treatment Centre network

pharmaceutical factory equipment working

The iMATCH consortium, led by Professor Fiona Thistlethwaite, is set to benefit from new funding announced for the Advanced Therapy Treatment Centre (ATTC) network.

Announced on the 21st March 2024, the funding for iMATCH is part of a wider £17.9 strategic initiative by National Institute for Health and Care Research (NIHR), Innovate UK, the Advanced Therapy Treatment Centre Network and the Cell and Gene Therapy Catapult (CGT Catapult) to enhance the UK environment for advanced therapy medicinal product (ATMP) clinical trials and to keep the UK as a location of choice for advanced therapy research.

The initiative will provide a further four years of funding for the Advanced Therapy Treatment Centre Network. The funding will come from NIHR, Innovate UK will provide oversight of the funds and CGT Catapult provide co-ordination of the network.

We are delighted to have achieved onward funding for the ATTC network including iMATCH. It means we will be able to progress the work we started in 2018 to scale up activity and overcome barriers in complex cell and gene therapies with Manchester at the heart of these developments. We’re now well-positioned to take gene and cell therapy research and treatment to the next step, move completely away from the more traditional one-size-fits-all approach, and improve personalised medicine for all our patients in the future.

Professor Fiona Thistlethwaite

Director of iMATCH

Speaking about the award of the funding, Professor Fiona Thistlethwaite said:

“We are delighted to have achieved onward funding for the ATTC network including iMATCH. It means we will be able to progress the work we started in 2018 to scale up activity and overcome barriers in complex cell and gene therapies with Manchester at the heart of these developments. We’re now well-positioned to take gene and cell therapy research and treatment to the next step, move completely away from the more traditional one-size-fits-all approach, and improve personalised medicine for all our patients in the future.”

“This funding represents a vote of confidence in our team and our vision, and we are committed to maximising its impact for the benefit of patients and the wider communities we serve. This is an exciting journey of innovation and discovery, with the goal of improving outcomes for individuals affected by hard-to treat cancers.”

 

About the Advanced Therapy Treatment Centre

The Advanced Therapy Treatment Centre network is currently composed of three centres: Innovate Manchester Advanced Therapy Centre Hub; Midlands-Wales Advanced Therapy Treatment Centre; and the Northern Alliance Advanced Therapies Treatment Centre, with the CGT Catapult providing co-ordination.

The UK is a world leader in ATMP clinical research with 175 ongoing trials being carried out here, and with 9% of global ATMP trials having representation in the UK. Many more products are in development and further action is needed to ensure that the NHS is able to bring advanced therapies to patients at scale across the UK. Through this further funding, and in close collaboration with NIHR infrastructure and the devolved equivalents, the ATTC network aims to build on its work on advanced therapy clinical trial readiness to ensure the UK maintains its position as a globally attractive location for clinical research.

Speaking about the funding for the ATTC, Health Minister Andrew Stephenson, said: “This investment reaffirms the UK’s position as a global leader in clinical research. It will help roll out revolutionary medical products more quickly, potentially treating the root cause of disorders and diseases like Alzheimer’s and cancer. Harnessing technological and digital innovations is one of our primary focuses under the first ever NHS Long Term Workforce Plan, enabling new and advanced ways of working.”

Dr Stella Peace, Executive Director for the Healthy Living and Agriculture Domain at Innovate UK, said: “From our initial investment to now overseeing the delivery of the new four-year programme, our goal is to ensure the UK maintains its global leadership in clinical research. Our commitment to fostering innovation and scientific advancements is crucial for sustaining this leadership. This drives medical breakthroughs, as well as strengthening the UK economy by attracting investments, generating high-skilled jobs, and positioning us at the forefront of transformative healthcare discoveries.”

Matthew Durdy, Chief Executive of the Cell and Gene Therapy Catapult commented: “Advanced therapies have the potential to transform healthcare, providing a range of new, lifechanging treatments to patients. Thanks to far-sighted investments, like this commitment by NIHR and the on-going support of Innovate UK, the UK is recognised globally as a pioneer in advanced therapies. With the continued great work of the ATTC network, we hope to further build the reputation of the UK.”